Forum de statistique: Measuring and understanding Biological Age

Le Forum de statistique organisé par Unisanté et le Département de Biologie Computationnelle (DBC) de l’UNIL a lieu huit fois par an. Toutes sortes de thématiques de statistiques liés à la recherche scientifique, que ce soit d’un point de vue théorique ou appliqué sont abordées lors de séminaires, donnés en anglais ou en français.

Le forum est ouvert aux chercheurs et chercheuses de toutes institutions. Toutes autres personnes intéressées sont également les bienvenues.

Les séminaires pourront être suivis en visioconférence. 

Thème du jour

Measuring and understanding Biological Age

Abstract: Biological age is a term increasingly used to refer to the idea that we age at different rates. Work has shown that measures of biological age can be developed, which are prognostic of future mortality. However, the field is still in its infancy, with research often showing statistically significant results, but less emphasis on their implications, or their causes. Peter will discuss penalised regression approaches to estimation of chronological age and (hidden) biological age in high dimensional -omics assays such as proteomics, using the highly  (11 -omics assays) annotated  ORCADES population cohort, and share results of their prognostic value, as well as considering the wider context and outlook for the field.

Intervenant

• Peter Joshi, University of Edinburgh

Biography

Peter worked as an UK actuary until 2010, performing a number of roles, including Chief Actuary at Standard Life, Strategy Director at Tesco Bank.  Until 2020, he was a Principal Investigator and tenured member of faculty at the University of Edinburgh, Centre for Global health Research, leading a research programme in the biomarkers of human lifespan and aging, especially genomic. In 2021, whilst remaining an Honorary Fellow at Edinburgh,  he returned to the commercial world, advising organisations on genomics, mortality risk, and the commercialisation of associated propositions. He is currently Chief Scientific Officer for Humanity Inc, a  start-up focused on measuring and slowing biological age, and advises Global gene Corp on the commercialisation of genomic propositions in an insurance context.

Vidéos

Retrouvez les enregistrements vidéo des séminaires passés ici.